Protein
chips, also known as protein microarrays are miniaturized and parallel assay
systems that contain small amounts of purified proteins in a high-density
format. They allow simultaneous determination of a great variety of analytes
from small amounts of samples within a single experiment.
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The chip
consists of a support surface such as a glass slide, nitrocellulose membrane,
bead, or microtiter plate to which an array of capture proteins is bound. Probe
molecules, typically labeled with a fluorescent dye are added to the array.
COVID-19 Impact Analysis:
The COVID-19
outbreak has impacted the global protein chip market positively. There has been
a high demand for protein microarray from diagnostics laboratory due to
COVID-19. In 2020, in the U.S., digital protein microarray platform for rapid
multiplex quantification of cytokines from critically ill COVID-19 patients
admitted to the intensive care unit (ICU) at the University of Michigan
Hospital helped in a personalized strategy guided by rapid cytokine assays. In April
2020, China developed a SARS-CoV-2 proteome microarray containing 18 out of 28
predicted proteins and applied it for characterization of IgG and IgM antibody
responses from 29 convalescent patients. These responses provide insights to
aid development of effective diagnostic, therapeutic, and vaccination
strategies. These developments are expected to foster growth of the market.
By technology, the analytical microarray segment held a major
share in the protein chip market in 2020, and is expected to continue this
trend during the forecast period.
On the basis of application, the antibody characterization segment
held a major share in the protein chip market in 2020, and is expected to
continue the trend during the forecast period. This is attributed to advantages
that include reduction in biological sample volume, high
sensitivity/specificity, and large data generation.
By end user, the academic & research institutes segment is the
major contributor expected to hold largest share during the forecast period.
Key Market Players
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Agilent Technologies Inc.
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Bio-Rad Laboratories, Inc.
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DANAHER CORPORATION
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Illumina, Inc.
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Merck KGAA
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Arrayit Corporation
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PerkinElmer Inc.
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QUOTIENT LIMITED
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RayBiotech Life Inc.
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Thermo Fisher Scientific, Inc.
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